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Analysis of polymorphisms, promoter methylation, and mRNA expression profile of maternal and placental P53 and P21 genes in preeclamptic and normotensive pregnant women

BACKGROUND: Preeclampsia (PE), as a multisystem disorder, is associated with maternal hypertension and proteinuria. Apoptosis seems to be involved in the pathophysiology of PE, although its precise pathogenic mechanisms are not well established. In this study, we aimed to identify the association be...

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Detalles Bibliográficos
Autores principales: Harati-Sadegh, Mahdiyeh, Kohan, Leila, Teimoori, Batool, Mehrabani, Mehrnaz, Salimi, Saeedeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842146/
https://www.ncbi.nlm.nih.gov/pubmed/31703578
http://dx.doi.org/10.1186/s12929-019-0586-x