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Curcumin derivative WZ35 inhibits tumor cell growth via ROS-YAP-JNK signaling pathway in breast cancer

BACKGROUND: Breast cancer is the most prevalent cancer among women worldwide. WZ35, an analog of curcumin, has been demonstrated to remarkably improve the pharmacokinetic profiles in vivo compared with curcumin. WZ35 exhibits promising antitumor activity in gastric cancer, HCC, colon cancer. However...

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Detalles Bibliográficos
Autores principales: Wang, Lihua, Wang, Canwei, Tao, Zheying, Zhao, Liqian, Zhu, Zheng, Wu, Wencan, He, Ye, Chen, Hong, Zheng, Bin, Huang, Xiangjie, Yu, Yun, Yang, Linjun, Liang, Guang, Cui, Ri, Chen, Tongke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842168/
https://www.ncbi.nlm.nih.gov/pubmed/31703744
http://dx.doi.org/10.1186/s13046-019-1424-4