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Guillain-Barre syndrome observed with adoptive transfer of lymphocytes genetically engineered with an NY-ESO-1 reactive T-cell receptor

BACKGROUND: Adoptive transfer of autologous T-lymphocytes transduced with a high affinity NY-ESO-1-reactive T-cell receptor (NY-ESO-1(c259) T-cells) has emerged as a promising therapeutic strategy for patients with refractory synovial sarcoma. Secondary autoimmune T-cell mediated toxicities can occu...

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Detalles Bibliográficos
Autores principales: Joseph, Jocelyn, Nathenson, Michael J., Trinh, Van Anh, Malik, Karan, Nowell, Erica, Carter, Kristen, Weathers, Shiao-Pei, Demetri, George D., Araujo, Dejka, Conley, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842215/
https://www.ncbi.nlm.nih.gov/pubmed/31703609
http://dx.doi.org/10.1186/s40425-019-0759-x