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ProtRank: bypassing the imputation of missing values in differential expression analysis of proteomic data

BACKGROUND: Data from discovery proteomic and phosphoproteomic experiments typically include missing values that correspond to proteins that have not been identified in the analyzed sample. Replacing the missing values with random numbers, a process known as “imputation”, avoids apparent infinite fo...

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Detalles Bibliográficos
Autores principales: Medo, Matúš, Aebersold, Daniel M., Medová, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842221/
https://www.ncbi.nlm.nih.gov/pubmed/31706265
http://dx.doi.org/10.1186/s12859-019-3144-3