GLUT-1 siRNA Enhances Radiosensitization Of Laryngeal Cancer Stem Cells Via Enhanced DNA Damage, Cell Cycle Redistribution, And Promotion Of Apoptosis In Vitro And In Vivo

BACKGROUND: Radiotherapy does not show good efficacy against laryngeal cancer due to radioresistance. Cancer stem cells (CSCs) are considered among the causes of radioresistance. Inhibition of glucose transporter-1 (GLUT-1) using GLUT-1 small interfering RNA (siRNA) may enhance the radiosensitivity...

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Detalles Bibliográficos
Autores principales: Zhong, Jiang-Tao, Yu, Qi, Zhou, Shui-Hong, Yu, Er, Bao, Yang-Yang, Lu, Zhong-Jie, Fan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842317/
https://www.ncbi.nlm.nih.gov/pubmed/31806998
http://dx.doi.org/10.2147/OTT.S221423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842317/
https://www.ncbi.nlm.nih.gov/pubmed/31806998
http://dx.doi.org/10.2147/OTT.S221423

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