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Upregulation of cannabinoid receptor type 2, but not TSPO, in senescence-accelerated neuroinflammation in mice: a positron emission tomography study

BACKGROUND: Microglial cells are activated in response to changes in brain homeostasis during aging, dementia, and stroke. Type 2 endocannabinoid receptors (CB2) and translocator protein 18 kD (TSPO) are considered to reflect distinct aspects of microglia-related neuroinflammatory responses in the b...

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Detalles Bibliográficos
Autores principales: Yamagishi, Satoru, Iga, Yurika, Nakamura, Masato, Takizawa, Chika, Fukumoto, Dai, Kakiuchi, Takeharu, Nishiyama, Shingo, Ohba, Hiroyuki, Tsukada, Hideo, Sato, Kohji, Ouchi, Yasuomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842455/
https://www.ncbi.nlm.nih.gov/pubmed/31707986
http://dx.doi.org/10.1186/s12974-019-1604-3