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Necroptosis regulates tumor repopulation after radiotherapy via RIP1/RIP3/MLKL/JNK/IL8 pathway

BACKGROUND: Tumor cell repopulation after radiotherapy is a major cause for the tumor radioresistance and recurrence. This study aims to investigate the underlying mechanism of tumor repopulation after radiotherapy, with focus on whether and how necroptosis takes part in this process. METHODS: Necro...

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Detalles Bibliográficos
Autores principales: Wang, Yiwei, Zhao, Minghui, He, Sijia, Luo, Yuntao, Zhao, Yucui, Cheng, Jin, Gong, Yanping, Xie, Jianzhu, Wang, Yulan, Hu, Binjie, Tian, Ling, Liu, Xinjian, Li, Chuanyuan, Huang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842489/
https://www.ncbi.nlm.nih.gov/pubmed/31706322
http://dx.doi.org/10.1186/s13046-019-1423-5