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Terminalia Arjuna bark extract impedes foam cell formation and promotes apoptosis in ox-LDL-stimulated macrophages by enhancing UPR-CHOP pathway

BACKGROUND: Increased macrophage and foam cell apoptosis during early atherogenesis retards plaque progression by impeding foam cell formation, suppressing inflammation and limiting lesion cellularity. Our previous in vitro study in THP1 macrophages demonstrated that Terminalia Arjuna (TA) attenuate...

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Detalles Bibliográficos
Autores principales: Bhansali, Shipra, Khatri, Shivani, Dhawan, Veena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842518/
https://www.ncbi.nlm.nih.gov/pubmed/31706299
http://dx.doi.org/10.1186/s12944-019-1119-z