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Developmental competence and antigen switch frequency can be uncoupled in Trypanosoma brucei

African trypanosomes use an extreme form of antigenic variation to evade host immunity, involving the switching of expressed variant surface glycoproteins by a stochastic and parasite-intrinsic process. Parasite development in the mammalian host is another feature of the infection dynamic, with tryp...

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Detalles Bibliográficos
Autores principales: McWilliam, Kirsty R., Ivens, Alasdair, Morrison, Liam J., Mugnier, Monica R., Matthews, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842576/
https://www.ncbi.nlm.nih.gov/pubmed/31636179
http://dx.doi.org/10.1073/pnas.1912711116