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Developmental competence and antigen switch frequency can be uncoupled in Trypanosoma brucei
African trypanosomes use an extreme form of antigenic variation to evade host immunity, involving the switching of expressed variant surface glycoproteins by a stochastic and parasite-intrinsic process. Parasite development in the mammalian host is another feature of the infection dynamic, with tryp...
Autores principales: | McWilliam, Kirsty R., Ivens, Alasdair, Morrison, Liam J., Mugnier, Monica R., Matthews, Keith R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842576/ https://www.ncbi.nlm.nih.gov/pubmed/31636179 http://dx.doi.org/10.1073/pnas.1912711116 |
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