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Asymmetric base-pair opening drives helicase unwinding dynamics

The opening of a Watson–Crick double helix is required for crucial cellular processes, including replication, repair, and transcription. It has long been assumed that RNA or DNA base pairs are broken by the concerted symmetric movement of complementary nucleobases. By analyzing thousands of base-pai...

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Detalles Bibliográficos
Autores principales: Colizzi, Francesco, Perez-Gonzalez, Cibran, Fritzen, Remi, Levy, Yaakov, White, Malcolm F., Penedo, J. Carlos, Bussi, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842596/
https://www.ncbi.nlm.nih.gov/pubmed/31628254
http://dx.doi.org/10.1073/pnas.1901086116