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Strategies For Targeting Chronic Myeloid Leukaemia Stem Cells

Chronic Myeloid Leukaemia is a myeloproliferative disorder driven by the t(9;22) chromosomal translocation coding for the chimeric protein BCR-ABL. CML treatment represents the paradigm of molecular therapy of cancer. Since the development of the tyrosine kinase inhibitor of the BCR-ABL kinase, the...

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Detalles Bibliográficos
Autores principales: Carrà, Giovanna, Cartellà, Antonio, Maffeo, Beatrice, Morotti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842740/
https://www.ncbi.nlm.nih.gov/pubmed/31807112
http://dx.doi.org/10.2147/BLCTT.S228815