Cargando…

Strategies For Targeting Chronic Myeloid Leukaemia Stem Cells

Chronic Myeloid Leukaemia is a myeloproliferative disorder driven by the t(9;22) chromosomal translocation coding for the chimeric protein BCR-ABL. CML treatment represents the paradigm of molecular therapy of cancer. Since the development of the tyrosine kinase inhibitor of the BCR-ABL kinase, the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carrà, Giovanna, Cartellà, Antonio, Maffeo, Beatrice, Morotti, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842740/ https://www.ncbi.nlm.nih.gov/pubmed/31807112 http://dx.doi.org/10.2147/BLCTT.S228815

Ejemplares similares

Inhibition of bromodomain and extra‐terminal proteins increases sensitivity to venetoclax in chronic lymphocytic leukaemia
por: Carrà, Giovanna, et al.
Publicado: (2019)

Tumor Suppressors in Chronic Lymphocytic Leukemia: From Lost Partners to Active Targets
por: Andreani, Giacomo, et al.
Publicado: (2020)

Non-Coding RNAs: The “Dark Side Matter” of the CLL Universe
por: Lingua, Marcello Francesco, et al.
Publicado: (2021)

Targeting few to help hundreds: JAK, MAPK and ROCK pathways as druggable targets in atypical chronic myeloid leukemia
por: Rocca, Stefania, et al.
Publicado: (2018)

Nuclear-cytoplasmic Shuttling in Chronic Myeloid Leukemia: Implications in Leukemia Maintenance and Therapy
por: Carrà, Giovanna, et al.
Publicado: (2019)

The non-genomic loss of function of tumor suppressors: an essential role in the pathogenesis of chronic myeloid leukemia chronic phase
por: Crivellaro, Sabrina, et al.
Publicado: (2016)

BCR-ABL Promotes PTEN Downregulation in Chronic Myeloid Leukemia
por: Panuzzo, Cristina, et al.
Publicado: (2014)

The Role of PTEN in Myeloid Malignancies
por: Morotti, Alessandro, et al.
Publicado: (2015)

Mechanisms of Resistance and Implications for Treatment Strategies in Chronic Myeloid Leukaemia
por: Poudel, Govinda, et al.
Publicado: (2022)

Targeting apoptosis in acute myeloid leukaemia
por: Cassier, Philippe A, et al.
Publicado: (2017)

Chronic Myeloid Leukaemia in The 21st Century
por: Frazer, Rachel, et al.
Publicado: (2007)

Clonal hematopoiesis by DNMT3A mutations as a common finding in idiopathic splanchnic vein thrombosis
por: Carrà, Giovanna, et al.
Publicado: (2022)

Antigenic Targets for the Immunotherapy of Acute Myeloid Leukaemia
por: Khan, Ghazala Naz, et al.
Publicado: (2019)

Targeting Apoptotic Pathways in Acute Myeloid Leukaemia
por: Sillar, Jonathan R., et al.
Publicado: (2019)

Emerging Therapeutic Strategies for Targeting Chronic Myeloid Leukemia Stem Cells
por: Hamad, Ahmad, et al.
Publicado: (2013)

Asciminib for chronic myeloid leukaemia
Publicado: (2022)

Dysregulation of haematopoietic stem cell regulatory programs in acute myeloid leukaemia
por: Basilico, Silvia, et al.
Publicado: (2017)

The underestimated role of basophils in Ph(+) chronic myeloid leukaemia
por: Valent, Peter, et al.
Publicado: (2018)

The Spliceosome: A New Therapeutic Target in Chronic Myeloid Leukaemia
por: Lebecque, Benjamin, et al.
Publicado: (2022)

Shedding Light on Targeting Chronic Myeloid Leukemia Stem Cells
por: Houshmand, Mohammad, et al.
Publicado: (2021)

Chronic myeloid leukaemia with marked thrombocytosis
por: Ooi, Jun, et al.
Publicado: (2020)

Prospects for achieving treatment‐free remission in chronic myeloid leukaemia
por: Saglio, Giuseppe, et al.
Publicado: (2020)

N6-Methyladenosine Role in Acute Myeloid Leukaemia
por: Ianniello, Zaira, et al.
Publicado: (2018)

IκBα targeting promotes oxidative stress-dependent cell death
por: Carrà, Giovanna, et al.
Publicado: (2021)

Insights into the optimal use of ponatinib in patients with chronic phase chronic myeloid leukaemia
por: Molica, Matteo, et al.
Publicado: (2019)

Paediatric chronic myeloid leukaemia: Is it really a different disease?
por: Pushpam, Deepam, et al.
Publicado: (2019)

Molecular techniques for the personalised management of patients with chronic myeloid leukaemia
por: Alikian, Mary, et al.
Publicado: (2017)

An overview of the role of platelets in angiogenesis, apoptosis and autophagy in chronic myeloid leukaemia
por: Repsold, Lisa, et al.
Publicado: (2017)

Consensus on BCR‐ABL1 reporting in chronic myeloid leukaemia in the UK
por: Cross, Nicholas C. P., et al.
Publicado: (2018)

Mitochondrial metabolism as a potential therapeutic target in myeloid leukaemia
por: de Beauchamp, Lucie, et al.
Publicado: (2021)

Clinical pathway for patients with Chronic Myeloid Leukaemia: The Euriclea Project
por: Botti, Stefano, et al.
Publicado: (2017)

COVID-19 in persons with chronic myeloid leukaemia
por: Li, Weiming, et al.
Publicado: (2020)

Isolated Ocular Manifestations in Chronic Myeloid Leukaemia
por: Maniam, Anita, et al.
Publicado: (2021)

Two ophthalmic presentations of chronic myeloid leukaemia
por: Kiernan, Miles, et al.
Publicado: (2022)

microRNA expression in acute myeloid leukaemia: New targets for therapy?
por: Fletcher, Daniel, et al.
Publicado: (2022)

Adhesion Deregulation in Acute Myeloid Leukaemia
por: Gruszka, Alicja M., et al.
Publicado: (2019)

Murine Models of Acute Myeloid Leukaemia
por: Almosailleakh, Marwa, et al.
Publicado: (2019)

Wnt Signalling in Acute Myeloid Leukaemia
por: Gruszka, Alicja M., et al.
Publicado: (2019)

Protein Kinase CK2: A Targetable BCR-ABL Partner in Philadelphia Positive Leukemias
por: Morotti, Alessandro, et al.
Publicado: (2015)

Acute Myeloid Leukaemia: New Targets and Therapies
por: Brown, Geoffrey, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ee6901v93s0ihfkuh5dlhf7vcb