Ubiquitination of the HPV Oncoprotein E6 Is Critical for E6/E6AP-Mediated p53 Degradation

High-risk Human papillomaviruses (HPVs) types are associated with more than 90% of premalignant and malignant squamous lesions of the uterine cervix. The E6 oncoprotein of high-risk HPVs is a key determinant in cell transformation because it induces the degradation of the host pro-apoptotic tumor su...

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Detalles Bibliográficos
Autores principales: Li, Siying, Hong, Xiaoling, Wei, Zhentong, Xie, Min, Li, Wanying, Liu, Guanchen, Guo, Haoran, Yang, Jiaxin, Wei, Wei, Zhang, Songling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842930/
https://www.ncbi.nlm.nih.gov/pubmed/31749782
http://dx.doi.org/10.3389/fmicb.2019.02483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842930/
https://www.ncbi.nlm.nih.gov/pubmed/31749782
http://dx.doi.org/10.3389/fmicb.2019.02483

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