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Structural Transition States Explored With Minimalist Coarse Grained Models: Applications to Calmodulin

Transitions between different conformational states are ubiquitous in proteins, being involved in signaling, catalysis, and other fundamental activities in cells. However, modeling those processes is extremely difficult, due to the need of efficiently exploring a vast conformational space in order t...

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Detalles Bibliográficos
Autores principales: Delfino, Francesco, Porozov, Yuri, Stepanov, Eugene, Tamazian, Gaik, Tozzini, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843051/
https://www.ncbi.nlm.nih.gov/pubmed/31750313
http://dx.doi.org/10.3389/fmolb.2019.00104