Reliable Generation of Native-Like Decoys Limits Predictive Ability in Fragment-Based Protein Structure Prediction

Our previous work with fragment-assembly methods has demonstrated specific deficiencies in conformational sampling behaviour that, when addressed through improved sampling algorithms, can lead to more reliable prediction of tertiary protein structure when good fragments are available, and when score...

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Detalles Bibliográficos
Autores principales: Kandathil, Shaun M., Garza-Fabre, Mario, Handl, Julia, Lovell, Simon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843117/
https://www.ncbi.nlm.nih.gov/pubmed/31618996
http://dx.doi.org/10.3390/biom9100612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843117/
https://www.ncbi.nlm.nih.gov/pubmed/31618996
http://dx.doi.org/10.3390/biom9100612

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