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Divergent Roles of CYP26B1 and Endogenous Retinoic Acid in Mouse Fetal Gonads
In female mammals, germ cells enter meiosis in the fetal ovaries, while in males, meiosis is prevented until postnatal development. Retinoic acid (RA) is considered the main inducer of meiotic entry, as it stimulates Stra8 which is required for the mitotic/meiotic switch. In fetal testes, the RA-deg...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843241/ https://www.ncbi.nlm.nih.gov/pubmed/31561560 http://dx.doi.org/10.3390/biom9100536 |