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Engineered Liver-On-A-Chip Platform to Mimic Liver Functions and Its Biomedical Applications: A Review

Hepatology and drug development for liver diseases require in vitro liver models. Typical models include 2D planar primary hepatocytes, hepatocyte spheroids, hepatocyte organoids, and liver-on-a-chip. Liver-on-a-chip has emerged as the mainstream model for drug development because it recapitulates t...

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Detalles Bibliográficos
Autores principales: Deng, Jiu, Wei, Wenbo, Chen, Zongzheng, Lin, Bingcheng, Zhao, Weijie, Luo, Yong, Zhang, Xiuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843249/
https://www.ncbi.nlm.nih.gov/pubmed/31591365
http://dx.doi.org/10.3390/mi10100676