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Cooperative Cellular Uptake and Activity of Octaarginine Antisense Peptide Nucleic Acid (PNA) Conjugates

Cellular uptake and antisense activity of d-octaarginine conjugated peptide nucleic acids (PNAs) is shown to exhibit pronounced cooperativity in serum-containing medium, in particular by being enhanced by analogous mis-match PNA–cell-penetrating peptide (PNA–CPP) conjugates without inherent antisens...

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Detalles Bibliográficos
Autores principales: Ghavami, Mahdi, Shiraishi, Takehiko, Nielsen, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843268/
https://www.ncbi.nlm.nih.gov/pubmed/31581514
http://dx.doi.org/10.3390/biom9100554