Bio-Guided Fractionation of Ethanol Extract of Leaves of Esenbeckia alata Kunt (Rutaceae) Led to the Isolation of Two Cytotoxic Quinoline Alkaloids: Evidence of Selectivity Against Leukemia Cells

Bio-guided fractionation performed on the leaves-derived ethanol extract of Esenbeckia alata (Rutaceae), a plant used in traditional medicine, led to the isolation of two alkaloids, kokusaginine 1 and flindersiamine 2, as main cytotoxic agents. Primary ethanolic extract and raw fractions exhibited c...

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Detalles Bibliográficos
Autores principales: Álvarez-Caballero, Juan Manuel, Cuca-Suárez, Luis Enrique, Coy-Barrera, Ericsson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843300/
https://www.ncbi.nlm.nih.gov/pubmed/31597257
http://dx.doi.org/10.3390/biom9100585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843300/
https://www.ncbi.nlm.nih.gov/pubmed/31597257
http://dx.doi.org/10.3390/biom9100585

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