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Linking Dysregulated AMPK Signaling and ER Stress in Ethanol-Induced Liver Injury in Hepatic Alcohol Dehydrogenase Deficient Deer Mice

Ethanol (EtOH) metabolism itself can be a predisposing factor for initiation of alcoholic liver disease (ALD). Therefore, a dose dependent study to evaluate liver injury was conducted in hepatic alcohol dehydrogenase (ADH) deficient (ADH(−)) and ADH normal (ADH(+)) deer mice fed 1%, 2% or 3.5% EtOH...

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Detalles Bibliográficos
Autores principales: Srinivasan, Mukund P., Bhopale, Kamlesh K., Amer, Samir M., Wan, Jie, Kaphalia, Lata, Ansari, Ghulam S., Kaphalia, Bhupendra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843321/
https://www.ncbi.nlm.nih.gov/pubmed/31581705
http://dx.doi.org/10.3390/biom9100560