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Hinge Region in DNA Packaging Terminase pUL15 of Herpes Simplex Virus: A Potential Allosteric Target for Antiviral Drugs

Approximately 80% of adults are infected with a member of the herpesviridae family. Herpesviruses establish life-long latent infections within neurons, which may reactivate into lytic infections due to stress or immune suppression. There are nine human herpesviruses (HHV) posing health concerns from...

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Detalles Bibliográficos
Autores principales: Thaljeh, Lana F., Rothschild, J. Ainsley, Naderi, Misagh, Coghill, Lyndon M., Brown, Jeremy M., Brylinski, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843332/
https://www.ncbi.nlm.nih.gov/pubmed/31614784
http://dx.doi.org/10.3390/biom9100603