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Flumequine-Mediated Upregulation of p38 MAPK and JNK Results in Melanogenesis in B16F10 Cells and Zebrafish Larvae

Flumequine is a well-known second generation quinolone antibiotic that induces phototoxicity. However, the effect of flumequine on skin melanogenesis is unclear. Therefore, we, for the first time, investigated whether flumequine regulates melanogenesis. The present study showed that flumequine sligh...

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Detalles Bibliográficos
Autores principales: Karunarathne, Wisurumuni Arachchilage Hasitha Maduranga, Molagoda, Ilandarage Menu Neelaka, Kim, Myung Sook, Choi, Yung Hyun, Oren, Matan, Park, Eui Kyun, Kim, Gi-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843389/
https://www.ncbi.nlm.nih.gov/pubmed/31614510
http://dx.doi.org/10.3390/biom9100596