The Link That Binds: The Linker of Hsp70 as a Helm of the Protein’s Function

The heat shock 70 (Hsp70) family of molecular chaperones plays a central role in maintaining cellular proteostasis. Structurally, Hsp70s are composed of an N-terminal nucleotide binding domain (NBD) which exhibits ATPase activity, and a C-terminal substrate binding domain (SBD). The binding of ATP a...

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Detalles Bibliográficos
Autores principales: Chakafana, Graham, Zininga, Tawanda, Shonhai, Addmore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843406/
https://www.ncbi.nlm.nih.gov/pubmed/31569820
http://dx.doi.org/10.3390/biom9100543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843406/
https://www.ncbi.nlm.nih.gov/pubmed/31569820
http://dx.doi.org/10.3390/biom9100543

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