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RhoA-Dependent HGF and c-Met Mediate Gas6-Induced Inhibition of Epithelial–Mesenchymal Transition, Migration, and Invasion of Lung Alveolar Epithelial Cells

Previously, we demonstrated that growth arrest-specific protein 6 (Gas6)/Axl or Mer signaling inhibited the transforming growth factor (TGF)-β1-induced epithelial–mesenchymal transition (EMT) in lung epithelial cells. Hepatocyte growth factor (HGF) has also been shown to inhibit TGF-β1-induced chang...

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Detalles Bibliográficos
Autores principales: Jung, Jihye, Yang, Kyungwon, Kim, Hee-Ja, Lee, Ye-Ji, Kim, Minsuk, Choi, Youn-Hee, Kang, Jihee Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843420/
https://www.ncbi.nlm.nih.gov/pubmed/31590238
http://dx.doi.org/10.3390/biom9100565