Cargando…

RhoA-Dependent HGF and c-Met Mediate Gas6-Induced Inhibition of Epithelial–Mesenchymal Transition, Migration, and Invasion of Lung Alveolar Epithelial Cells

Previously, we demonstrated that growth arrest-specific protein 6 (Gas6)/Axl or Mer signaling inhibited the transforming growth factor (TGF)-β1-induced epithelial–mesenchymal transition (EMT) in lung epithelial cells. Hepatocyte growth factor (HGF) has also been shown to inhibit TGF-β1-induced chang...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jung, Jihye, Yang, Kyungwon, Kim, Hee-Ja, Lee, Ye-Ji, Kim, Minsuk, Choi, Youn-Hee, Kang, Jihee Lee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843420/ https://www.ncbi.nlm.nih.gov/pubmed/31590238 http://dx.doi.org/10.3390/biom9100565

Ejemplares similares

Gas6 Prevents Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells via Production of PGE(2), PGD(2) and Their Receptors
por: Jung, Jihye, et al.
Publicado: (2019)

The TAM-family receptor Mer mediates production of HGF through the RhoA-dependent pathway in response to apoptotic cells
por: Park, Hyun-Jung, et al.
Publicado: (2012)

Macrophages programmed by apoptotic cells inhibit epithelial-mesenchymal transition in lung alveolar epithelial cells via PGE(2), PGD(2), and HGF
por: Yoon, Young-So, et al.
Publicado: (2016)

Paeoniflorin Inhibits Hepatocyte Growth Factor- (HGF-) Induced Migration and Invasion and Actin Rearrangement via Suppression of c-Met-Mediated RhoA/ROCK Signaling in Glioblastoma
por: Yu, Guoyong, et al.
Publicado: (2019)

Gab2 regulates cytoskeletal organization and migration of mammary epithelial cells by modulating RhoA activation
por: Abreu, Maria Teresa Herrera, et al.
Publicado: (2011)

Increased intracellular Cl(-) concentration improves airway epithelial migration by activating the RhoA/ROCK Pathway
por: Huang, Wenjie, et al.
Publicado: (2020)

RhoA GTPase inhibition organizes contraction during epithelial morphogenesis
por: Mason, Frank M., et al.
Publicado: (2016)

Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion
por: Cao, Hui-Hui, et al.
Publicado: (2015)

Apoptosis inhibitor of macrophage (AIM) contributes to IL-10-induced anti-inflammatory response through inhibition of inflammasome activation
por: Kim, Tae-Hyun, et al.
Publicado: (2021)

MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell–cell junctions in epithelial cells
por: Breznau, Elaina B., et al.
Publicado: (2015)

Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility
por: Li, Ran, et al.
Publicado: (2015)

Regulation of RhoA activity by the cellular prion protein
por: Kim, Hee-Jun, et al.
Publicado: (2017)

Influenza induces IL-8 and GM-CSF secretion by human alveolar epithelial cells through HGF/c-Met and TGF-α/EGFR signaling
por: Ito, Yoko, et al.
Publicado: (2015)

The Involvement of RhoA and Wnt-5a in the Tumorigenesis and Progression of Ovarian Epithelial Carcinoma
por: Chen, Shuo, et al.
Publicado: (2013)

EpCAM promotes endosomal modulation of the cortical RhoA zone for epithelial organization
por: Gaston, Cécile, et al.
Publicado: (2021)

Type II alveolar epithelial cell–specific loss of RhoA exacerbates allergic airway inflammation through SLC26A4
por: Do, Danh C., et al.
Publicado: (2021)

Spatially restricted activation of RhoA at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis
por: Terry, Stephen J., et al.
Publicado: (2011)

Loss of the obscurin-RhoGEF downregulates RhoA signaling and increases microtentacle formation and attachment of breast epithelial cells
por: Perry, Nicole A., et al.
Publicado: (2014)

MicroRNA-182 Suppresses HGF/SF-Induced Increases in Retinal Pigment Epithelial Cell Proliferation and Migration through Targeting c-Met
por: Wang, Lihua, et al.
Publicado: (2016)

HGF and c-Met Interaction Promotes Migration in Human Chondrosarcoma Cells
por: Tsou, Hsi-Kai, et al.
Publicado: (2013)

Evidence for the Involvement of RhoA Signaling in the Ethanol-Induced Increase in Intestinal Epithelial Barrier Permeability
por: Tong, Jing, et al.
Publicado: (2013)

Desmosome-anchored intermediate filaments facilitate tension-sensitive RhoA signaling for epithelial homeostasis
por: Nanavati, Bageshri Naimish, et al.
Publicado: (2023)

RhoA/Rho-kinase triggers epithelial-mesenchymal transition in mesothelial cells and contributes to the pathogenesis of dialysis-related peritoneal fibrosis
por: Wang, Qinglian, et al.
Publicado: (2018)

Dynamic functions of RhoA in tumor cell migration and invasion
por: O'Connor, Kathleen, et al.
Publicado: (2013)

HGF/MET Regulated Epithelial-Mesenchymal Transitions And Metastasis By FOSL2 In Non-Small Cell Lung Cancer
por: Yin, Jun, et al.
Publicado: (2019)

HGF/c-Met signaling promotes the migration and proliferation of deer antler MSCs
por: Wang, Miao, et al.
Publicado: (2023)

A RhoC Biosensor Reveals Differences in the Activation Kinetics of RhoA and RhoC in Migrating Cells
por: Zawistowski, Jon S., et al.
Publicado: (2013)

Activin B Promotes Epithelial Wound Healing In Vivo through RhoA-JNK Signaling Pathway
por: Zhang, Min, et al.
Publicado: (2011)

RhoA/ROCK pathway mediates the effect of oestrogen on regulating epithelial‐mesenchymal transition and proliferation in endometriosis
por: Huang, Zhi‐Xiong, et al.
Publicado: (2020)

Ouabain Induces Transcript Changes and Activation of RhoA/ROCK Signaling in Cultured Epithelial Cells (MDCK)
por: Martínez-Rendón, Jacqueline, et al.
Publicado: (2023)

Histone deacetylase 3 promotes alveolar epithelial–mesenchymal transition and fibroblast migration under hypoxic conditions
por: Jeong, Sung Hwan, et al.
Publicado: (2022)

Protein Kinase A Governs a RhoA-RhoGDI Protrusion-Retraction Pacemaker in Migrating Cells
por: Tkachenko, Eugene, et al.
Publicado: (2011)

Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling
por: Zhang, Jason Z., et al.
Publicado: (2020)

Calsenilin, a Presenilin Interactor, Regulates RhoA Signaling and Neurite Outgrowth
por: Kim, Hee-Jun, et al.
Publicado: (2018)

RhoA improves cryopreservation of rooster sperm through the Rho/RhoA-associated kinase/cofilin pathway
por: Heng, Nuo, et al.
Publicado: (2022)

Vitamin D Proliferates Vaginal Epithelium through RhoA Expression in Postmenopausal Atrophic Vagina tissue
por: Lee, Arum, et al.
Publicado: (2017)

RhoA is required for monocyte tail retraction during transendothelial migration
por: Worthylake, Rebecca A., et al.
Publicado: (2001)

Flowtaxis of osteoblast migration under fluid shear and the effect of RhoA kinase silencing
por: Riehl, Brandon D., et al.
Publicado: (2017)

Rap1 regulates hepatic stellate cell migration through the modulation of RhoA activity in response to TGF-β1
por: Moon, Mi-Young, et al.
Publicado: (2019)

Pre-Osteoblasts Stimulate Migration of Breast Cancer Cells via the HGF/MET Pathway
por: Vallet, Sonia, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_jpfnuj2m2hi0ikcchp6l5on62o