YAP Inhibition by Nuciferine via AMPK-Mediated Downregulation of HMGCR Sensitizes Pancreatic Cancer Cells to Gemcitabine

Nuciferine, a major aporphine alkaloid constituent of lotus leaves, is a raw material for obesity treatment. Extensive studies have revealed that obesity is associated with pancreatic cancer (PC). However, it has not been clarified whether nuciferine could be used in PC treatment or prevention. Here...

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Detalles Bibliográficos
Autores principales: Zhou, Ling, Wang, Qiaoyun, Zhang, Han, Li, Youjie, Xie, Shuyang, Xu, Maolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843496/
https://www.ncbi.nlm.nih.gov/pubmed/31627466
http://dx.doi.org/10.3390/biom9100620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843496/
https://www.ncbi.nlm.nih.gov/pubmed/31627466
http://dx.doi.org/10.3390/biom9100620

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