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Sustained Neurotrophin Release from Protein Nanoparticles Mediated by Matrix Metalloproteinases Induces the Alignment and Differentiation of Nerve Cells

The spatial and temporal availability of cytokines, and the microenvironments this creates, is critical to tissue development and homeostasis. Creating concentration gradients in vitro using soluble proteins is challenging as they do not provide a self-sustainable source. To mimic the sustained cyto...

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Detalles Bibliográficos
Autores principales: Matsuzaki, Yuka, Maruta, Rina, Takaki, Keiko, Kotani, Eiji, Kato, Yasuko, Yoshimura, Ryoichi, Endo, Yasuhisa, Whitty, Ciara, Pernstich, Christian, Gandhi, Raj, Jones, Michael, Mori, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843502/
https://www.ncbi.nlm.nih.gov/pubmed/31546991
http://dx.doi.org/10.3390/biom9100510