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Sustained Neurotrophin Release from Protein Nanoparticles Mediated by Matrix Metalloproteinases Induces the Alignment and Differentiation of Nerve Cells
The spatial and temporal availability of cytokines, and the microenvironments this creates, is critical to tissue development and homeostasis. Creating concentration gradients in vitro using soluble proteins is challenging as they do not provide a self-sustainable source. To mimic the sustained cyto...
Autores principales: | Matsuzaki, Yuka, Maruta, Rina, Takaki, Keiko, Kotani, Eiji, Kato, Yasuko, Yoshimura, Ryoichi, Endo, Yasuhisa, Whitty, Ciara, Pernstich, Christian, Gandhi, Raj, Jones, Michael, Mori, Hajime |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843502/ https://www.ncbi.nlm.nih.gov/pubmed/31546991 http://dx.doi.org/10.3390/biom9100510 |
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