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The Effect of Dimethyl Sulfoxide on the Lysozyme Unfolding Kinetics, Thermodynamics, and Mechanism

The thermal stability of proteins in the presence of organic solvents and the search for ways to increase this stability are important topics in industrial biocatalysis and protein engineering. The denaturation of hen egg-white lysozyme in mixtures of water with dimethyl sulfoxide (DMSO) with a broa...

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Detalles Bibliográficos
Autores principales: Magsumov, Timur, Fatkhutdinova, Alisa, Mukhametzyanov, Timur, Sedov, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843525/
https://www.ncbi.nlm.nih.gov/pubmed/31569484
http://dx.doi.org/10.3390/biom9100547