Effects of Single Nucleotide Polymorphism Ala270Ser (rs316019) on the Function and Regulation of hOCT2

The human organic cation transporter 2 (hOCT2) is highly expressed in proximal tubules of the kidneys, where it plays an important role in the secretion of organic cations. Since many drugs are organic cations, hOCT2 has relevant pharmacological implications. The hOCT2 gene is polymorphic, and the n...

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Detalles Bibliográficos
Autores principales: Frenzel, Dominik, Köppen, Christina, Bolle Bauer, Oliver, Karst, Uwe, Schröter, Rita, Tzvetkov, Mladen V., Ciarimboli, Giuliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843571/
https://www.ncbi.nlm.nih.gov/pubmed/31591331
http://dx.doi.org/10.3390/biom9100578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843571/
https://www.ncbi.nlm.nih.gov/pubmed/31591331
http://dx.doi.org/10.3390/biom9100578

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