Whole Genome Sequencing of Familial Non-Medullary Thyroid Cancer Identifies Germline Alterations in MAPK/ERK and PI3K/AKT Signaling Pathways

Evidence of familial inheritance in non-medullary thyroid cancer (NMTC) has accumulated over the last few decades. However, known variants account for a very small percentage of the genetic burden. Here, we focused on the identification of common pathways and networks enriched in NMTC families to be...

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Detalles Bibliográficos
Autores principales: Srivastava, Aayushi, Kumar, Abhishek, Giangiobbe, Sara, Bonora, Elena, Hemminki, Kari, Försti, Asta, Bandapalli, Obul Reddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843654/
https://www.ncbi.nlm.nih.gov/pubmed/31614935
http://dx.doi.org/10.3390/biom9100605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843654/
https://www.ncbi.nlm.nih.gov/pubmed/31614935
http://dx.doi.org/10.3390/biom9100605

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