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Upregulated Expression of Macrophage Migration Inhibitory Factor, Its Analogue D-Dopachrome Tautomerase, and the CD44 Receptor in Peripheral CD4 T Cells from Clinically Isolated Syndrome Patients with Rapid Conversion to Clinical Defined Multiple Sclerosis

Background and objectives: Macrophage Migration Inhibitory Factor (MIF) and D-Dopachrome Tautomerase (DDT) are two pleiotropic and primarily, but not exclusively, proinflammatory cytokines belonging to the MIF family of cytokines that have recently been shown to be implicated in the pathogenesis of...

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Detalles Bibliográficos
Autores principales: Cavalli, Eugenio, Mazzon, Emanuela, Basile, Maria Sofia, Mangano, Katia, Di Marco, Roberto, Bramanti, Placido, Nicoletti, Ferdinando, Fagone, Paolo, Petralia, Maria Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843666/
https://www.ncbi.nlm.nih.gov/pubmed/31581595
http://dx.doi.org/10.3390/medicina55100667