Statistically Designed Medium Reveals Interactions between Metabolism and Genetic Information Processing for Production of Stable Human Serum Albumin in Pichia pastoris

Human serum albumin (HSA), sourced from human serum, has been an important therapeutic protein for several decades. Pichia pastoris is strongly considered as an expression platform, but proteolytic degradation of recombinant HSA in the culture filtrate remains a major bottleneck for use of this syst...

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Detalles Bibliográficos
Autores principales: Maity, Nitu, Mishra, Saroj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843683/
https://www.ncbi.nlm.nih.gov/pubmed/31590267
http://dx.doi.org/10.3390/biom9100568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843683/
https://www.ncbi.nlm.nih.gov/pubmed/31590267
http://dx.doi.org/10.3390/biom9100568

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