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Kinetic Transition in Amyloid Assembly as a Screening Assay for Oligomer-Selective Dyes

Assembly of amyloid fibrils and small globular oligomers is associated with a significant number of human disorders that include Alzheimer’s disease, senile systemic amyloidosis, and type II diabetes. Recent findings implicate small amyloid oligomers as the dominant aggregate species mediating the t...

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Detalles Bibliográficos
Autores principales: Barton, Jeremy, Arias, D. Sebastian, Niyangoda, Chamani, Borjas, Gustavo, Le, Nathan, Mohamed, Saefallah, Muschol, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843685/
https://www.ncbi.nlm.nih.gov/pubmed/31569739
http://dx.doi.org/10.3390/biom9100539