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Disorder-to-Order Markers of a Cyclic Hexapeptide Inspired from the Binding Site of Fertilin β Involved in Fertilization Process

[Image: see text] Synthetic peptides mimicking the binding site of fertilin β to its receptor, integrin α6β1, were shown to inhibit sperm–egg fusion when added to in vitro media. In contrast, the synthetic cyclic hexapeptide, cyclo(Cys(1)-Ser(2)-Phe(3)-Glu(4)-Glu(5)-Cys(6)), named as cFEE, proved to...

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Detalles Bibliográficos
Autores principales: Henández, Belén, Legrand, Pauline, Dufay, Sophie, Gahoual, Rabah, Sanchez-Cortes, Santiago, Kruglik, Sergei G., Fabreguettes, Jean-Roch, Wolf, Jean-Philippe, Houzé, Pascal, Ghomi, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843708/
https://www.ncbi.nlm.nih.gov/pubmed/31720508
http://dx.doi.org/10.1021/acsomega.9b01885