Pharmacokinetics and Metabolite Profiling of Trepibutone in Rats Using Ultra-High Performance Liquid Chromatography Combined With Hybrid Quadrupole-Orbitrap and Triple Quadrupole Mass Spectrometers

Trepibutone was widely used for cholelithiasis, cholecystitis, biliary tract dyskinesia, cholecystectomy syndrome, and chronic pancreatitis in clinic. However, few investigations on trepibutone have been conducted. In this study, an accurate, sensitive, and selective analytical method was developed...

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Detalles Bibliográficos
Autores principales: Sun, Zhi, Yang, Jie, Liu, Liwei, Xu, Yanyan, Zhou, Lin, Jia, Qingquan, Shi, Yingying, Du, Xiangyu, Kang, Jian, Zuo, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843799/
https://www.ncbi.nlm.nih.gov/pubmed/31749700
http://dx.doi.org/10.3389/fphar.2019.01266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843799/
https://www.ncbi.nlm.nih.gov/pubmed/31749700
http://dx.doi.org/10.3389/fphar.2019.01266

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