A Crucial Role for Ergosterol in Plasma Membrane Composition, Localisation, and Activity of Cdr1p and H(+)-ATPase in Candida albicans

Candida albicans is an opportunistic fungal pathogen of humans. Treatment of C. albicans infections relies on azoles, which target the lanosterol 14α-demethylase (Erg11p) encoded by the ERG11 gene. Our results show that targeted gene disruption of ERG11 can result in resistance to ergosterol-depende...

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Detalles Bibliográficos
Autores principales: Suchodolski, Jakub, Muraszko, Jakub, Bernat, Przemysław, Krasowska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843828/
https://www.ncbi.nlm.nih.gov/pubmed/31546699
http://dx.doi.org/10.3390/microorganisms7100378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843828/
https://www.ncbi.nlm.nih.gov/pubmed/31546699
http://dx.doi.org/10.3390/microorganisms7100378

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