Cargando…
A Crucial Role for Ergosterol in Plasma Membrane Composition, Localisation, and Activity of Cdr1p and H(+)-ATPase in Candida albicans
Candida albicans is an opportunistic fungal pathogen of humans. Treatment of C. albicans infections relies on azoles, which target the lanosterol 14α-demethylase (Erg11p) encoded by the ERG11 gene. Our results show that targeted gene disruption of ERG11 can result in resistance to ergosterol-depende...
Autores principales: | Suchodolski, Jakub, Muraszko, Jakub, Bernat, Przemysław, Krasowska, Anna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843828/ https://www.ncbi.nlm.nih.gov/pubmed/31546699 http://dx.doi.org/10.3390/microorganisms7100378 |
Ejemplares similares
-
Lactate Like Fluconazole Reduces Ergosterol Content in the Plasma Membrane and Synergistically Kills Candida albicans
por: Suchodolski, Jakub, et al.
Publicado: (2021) -
The Role of Ergosterol and Sphingolipids in the Localization and Activity of Candida albicans’ Multidrug Transporter Cdr1p and Plasma Membrane ATPase Pma1p
por: Urbanek, Aneta K., et al.
Publicado: (2022) -
Lipid composition and cell surface hydrophobicity of Candida albicans influence the efficacy of fluconazole–gentamicin treatment
por: Suchodolski, Jakub, et al.
Publicado: (2020) -
Fructose Induces Fluconazole Resistance in Candida albicans through Activation of Mdr1 and Cdr1 Transporters
por: Suchodolski, Jakub, et al.
Publicado: (2021) -
Fluconazole and Lipopeptide Surfactin Interplay During Candida albicans Plasma Membrane and Cell Wall Remodeling Increases Fungal Immune System Exposure
por: Suchodolski, Jakub, et al.
Publicado: (2020)