Synthesis of Novel Analogs of Thieno[2,3-d] Pyrimidin-4(3H)-ones as Selective Inhibitors of Cancer Cell Growth

New 2,3-disubstituted thieno[2,3-d]pyrimidin-4(3H)-ones were synthesized via a one-pot reaction from 2H-thieno[2,3-d] [1,3]oxazine-2,4(1H)-diones, aromatic aldehydes, and benzylamine or 4-hydroxylbezylamine. The obtained compounds were tested in vitro for cancer cell growth inhibition. Compound 19 c...

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Detalles Bibliográficos
Autores principales: Zhang, Sheng, Liu, Feize, Hou, Xueling, Cao, Jianguo, Dai, Xiling, Yu, Junjie, Huang, Guozheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843832/
https://www.ncbi.nlm.nih.gov/pubmed/31640194
http://dx.doi.org/10.3390/biom9100631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843832/
https://www.ncbi.nlm.nih.gov/pubmed/31640194
http://dx.doi.org/10.3390/biom9100631

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