Histone deacetylase inhibition up-regulates MHC class I to facilitate cytotoxic T lymphocyte-mediated tumor cell killing in glioma cells

Background: Immune cells recognize tumor antigens presented on major histocompatibility complex class I (MHC-I) molecule. Increase of MHC-I molecular expression makes tumor cells more susceptible to lysis by immune cells. Methods: Tumor lysate vaccine was prepared to damage glioma cells including ce...

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Detalles Bibliográficos
Autores principales: Sun, Ting, Li, Yanyan, Yang, Wei, Wu, Haibin, Li, Xuetao, Huang, Yulun, Zhou, Youxin, Du, Ziwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843866/
https://www.ncbi.nlm.nih.gov/pubmed/31737100
http://dx.doi.org/10.7150/jca.34471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843866/
https://www.ncbi.nlm.nih.gov/pubmed/31737100
http://dx.doi.org/10.7150/jca.34471

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