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Histone deacetylase inhibition up-regulates MHC class I to facilitate cytotoxic T lymphocyte-mediated tumor cell killing in glioma cells

Background: Immune cells recognize tumor antigens presented on major histocompatibility complex class I (MHC-I) molecule. Increase of MHC-I molecular expression makes tumor cells more susceptible to lysis by immune cells. Methods: Tumor lysate vaccine was prepared to damage glioma cells including ce...

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Detalles Bibliográficos
Autores principales:	Sun, Ting, Li, Yanyan, Yang, Wei, Wu, Haibin, Li, Xuetao, Huang, Yulun, Zhou, Youxin, Du, Ziwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843866/ https://www.ncbi.nlm.nih.gov/pubmed/31737100 http://dx.doi.org/10.7150/jca.34471

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