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Overexpression of miR-4433 by suberoylanilide hydroxamic acid suppresses growth of CML cells and induces apoptosis through targeting Bcr-Abl

Background: Targeting Bcr-Abl is the key for the treatment of CML. Although great progress has been achieved for the treatment of CML patients in chronic stage, effective drugs with good safety are not available for those in advanced stages of CML patients. In present study, a histone deacetylase in...

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Detalles Bibliográficos
Autores principales: Wu, Haiyan, Yin, Jingyi, Ai, Zhengdong, Li, Guiming, Li, Yan, Chen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843884/
https://www.ncbi.nlm.nih.gov/pubmed/31737104
http://dx.doi.org/10.7150/jca.34972