Technical advance in targeted NGS analysis enables identification of lung cancer risk-associated low frequency TP53, PIK3CA, and BRAF mutations in airway epithelial cells

BACKGROUND: Standardized Nucleic Acid Quantification for SEQuencing (SNAQ-SEQ) is a novel method that utilizes synthetic DNA internal standards spiked into each sample prior to next generation sequencing (NGS) library preparation. This method was applied to analysis of normal appearing airway epithe...

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Detalles Bibliográficos
Autores principales: Craig, Daniel J., Morrison, Thomas, Khuder, Sadik A., Crawford, Erin L., Wu, Leihong, Xu, Joshua, Blomquist, Thomas M., Willey, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844032/
https://www.ncbi.nlm.nih.gov/pubmed/31711466
http://dx.doi.org/10.1186/s12885-019-6313-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844032/
https://www.ncbi.nlm.nih.gov/pubmed/31711466
http://dx.doi.org/10.1186/s12885-019-6313-x

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