Formation of compound I in heme bound Aβ-peptides relevant to Alzheimer's disease

Proteolysis of Amyloid Precursor Protein, APP, results in the formation of amyloid β (Aβ) peptides, which have been associated with Alzheimer's disease (AD). Recently the failure of therapeutic agents that prohibit Aβ aggregation and sequester Cu/Zn in providing symptomatic relief to AD patient...

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Detalles Bibliográficos
Autores principales: Pal, Ishita, Nath, Arnab Kumar, Roy, Madhuparna, Seal, Manas, Ghosh, Chandradeep, Dey, Abhishek, Dey, Somdatta Ghosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844219/
https://www.ncbi.nlm.nih.gov/pubmed/31803419
http://dx.doi.org/10.1039/c9sc01679a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844219/
https://www.ncbi.nlm.nih.gov/pubmed/31803419
http://dx.doi.org/10.1039/c9sc01679a

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