DNA-PKcs Mediates An Epithelial-Mesenchymal Transition Process Promoting Cutaneous Squamous Cell Carcinoma Invasion And Metastasis By Targeting The TGF-β1/Smad Signaling Pathway

PURPOSE: DNA-dependent protein kinase catalytic subunit (DNA-PKcs) has attracted extensive attention in various types of malignant tumors. However, the role of DNA-PKcs in cutaneous squamous cell carcinoma (cSCC) development has not been elucidated. In this study, we investigated the role of DNA-PKc...

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Detalles Bibliográficos
Autores principales: Zhang, Juan, Jiang, Hui, Xu, Dan, Wu, Wen-Juan, Chen, Hong-Duo, He, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844265/
https://www.ncbi.nlm.nih.gov/pubmed/31807020
http://dx.doi.org/10.2147/OTT.S205017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844265/
https://www.ncbi.nlm.nih.gov/pubmed/31807020
http://dx.doi.org/10.2147/OTT.S205017

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