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PD-L1 regulation by SDH5 via β-catenin/ZEB1 signaling

Programmed death-ligand 1 (PD-L1) is a crucial target for lung cancer immunotherapy. In lung cancer patients with high PD-L1 expression, blocking or reducing its expression can inhibit tumor growth. PD-L1 is regulated by signaling pathways, transcription factors and epigenetic factors, such as the G...

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Detalles Bibliográficos
Autores principales: Tuo, Zhan, Zong, Yan, Li, Jie, Xiao, Guangqin, Zhang, Furong, Li, Guiling, Wang, Sihua, Lv, Yi, Xia, Jiahong, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844322/
https://www.ncbi.nlm.nih.gov/pubmed/31741753
http://dx.doi.org/10.1080/2162402X.2019.1655361