The leucine biosynthetic pathway is crucial for adaptation to iron starvation and virulence in Aspergillus fumigatus

In contrast to mammalia, fungi are able to synthesize the branched-chain amino acid leucine de novo. Recently, the transcription factor LeuB has been shown to cross-regulate leucine biosynthesis, nitrogen metabolism and iron homeostasis in Aspergillus fumigatus, the most common human mold pathogen....

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Detalles Bibliográficos
Autores principales: Orasch, Thomas, Dietl, Anna-Maria, Shadkchan, Yana, Binder, Ulrike, Bauer, Ingo, Lass-Flörl, Cornelia, Osherov, Nir, Haas, Hubertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844326/
https://www.ncbi.nlm.nih.gov/pubmed/31694453
http://dx.doi.org/10.1080/21505594.2019.1682760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844326/
https://www.ncbi.nlm.nih.gov/pubmed/31694453
http://dx.doi.org/10.1080/21505594.2019.1682760

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