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The leucine biosynthetic pathway is crucial for adaptation to iron starvation and virulence in Aspergillus fumigatus
In contrast to mammalia, fungi are able to synthesize the branched-chain amino acid leucine de novo. Recently, the transcription factor LeuB has been shown to cross-regulate leucine biosynthesis, nitrogen metabolism and iron homeostasis in Aspergillus fumigatus, the most common human mold pathogen....
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844326/ https://www.ncbi.nlm.nih.gov/pubmed/31694453 http://dx.doi.org/10.1080/21505594.2019.1682760 |