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Expression of Tumor-mediated CD137 ligand in human colon cancer indicates dual signaling effects

CD137-targeting immune therapy, which activates anti-tumor T effector cell responses, seems to be an attractive concept in clinical oncology. Recent evidence has demonstrated that tumor cells besides T cells and antigen-presenting cells are able to express CD137 and CD137L. Here we aimed to identify...

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Detalles Bibliográficos
Autores principales: Grimmig, Tanja, Gasser, Martin, Moench, Romana, Zhu, Lang-Jing, Nawalaniec, Karol, Callies, Simone, Wagner, Martin, Polat, Buelent, Mothi, Suraj Sarvode, Luo, Yueming, Ribas, Carmen M., Malafaia, Osvaldo, Hsiao, Li-Li, Waaga-Gasser, Ana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844327/
https://www.ncbi.nlm.nih.gov/pubmed/31741755
http://dx.doi.org/10.1080/2162402X.2019.1651622